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If this is true, then it is likely that either the upregulated process of melanin biosynthesis, the increased amount of melanin in the melanocytes, or both, occurring in the fields of benign oral melanin hyperpigmentation, constitute risk factors for transformation into oral mucosal melanomata

The TGA says: We will continue to take strong enforcement actions to address unlawful advertising and supply of therapeutic goods consistent with our regulatory compliance framework. The manufacturers of these products claim they contain substances that are prescription-only medications

Cycle Length: 4 weeks of daily dosing, followed by 24 weeks off to evaluate progress and allow receptor resetting

Most side effects resolve within 12 weeks