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GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) effectively manage type 2 diabetes and promote weight loss, but their gastrointestinal effectsincluding nausea, vomiting, and diarrheacan disrupt fluid and electrolyte balance
For those with type 2 diabetes , your healthcare team may recommend several strategies: Individualised medication plan : Specific guidance for each of your diabetes medications (metformin, sulfonylureas, SGLT2 inhibitors, insulin) following established UK protocols Enhanced blood glucose monitoring : More frequent self-monitoring to identify any changes in control Dietary consistency : Maintaining regular eating patterns where possible Clear targets : Typical perioperative blood glucose targets are 6-10 mmol/L (with an acceptable range of 4-12 mmol/L) [2] SGLT2 inhibitors (medications ending in '-flozin') are typically stopped 3 days before surgery to reduce the risk of diabetic ketoacidosis, according to UK guidance
Early blood transfusions consisted of whole blood, but modern medical practice commonly uses only components of the blood, such as packed red blood cells, fresh frozen plasma or cryoprecipitate
