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Pfizer Sector: Pharmaceuticals & vaccines HQ: Rocky Mount, NC Year Founded: 1849 Key Leaders: Albert Bourla, Chairman and CEO

Given the limited efficacy of current anti-fibrotic therapies and the substantial morbidity associated with progressive pulmonary fibrosis, identification of novel pathways capable of modulating fibroblast activation and ECM remodelling remains a major therapeutic priority

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An Agilent ZORBAX Eclipse Plus C18 (2.1 mm 50 mm, 1.8 m) was used as an analytical column, and an Agilent ZORBAX StableBond-C8 (2.1 mm 5 mm, 1.8 m) (Agilent, Santa Clara, CA, USA) was used as a guard column