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Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel

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0.1% RGN-259 (Thymosin 4) ophthalmic solution promotes healing and improves comfort in neurotrophic keratopathy patients in a randomized, placebo-controlled, double-masked Phase III clinical trial

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however, it enhances glucagon release during normoglycemia or hypoglycemia

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From around June 2026, criteria are expected to broaden to include people with a BMI of 35 or above with four qualifying conditions

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