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The case of the 23-year-old woman who developed alopecia areata two months after starting semaglutide demonstrates that GLP-1 medications can potentially trigger autoimmune hair loss in susceptible individuals
The IL-17 secreted by these cells binds to IL-17 receptors (IL-17Rs) expressed in midbrain neurons, inducing neuronal death through the upregulation of NF-B and downstream signaling pathways, as demonstrated in human iPSC-derived neuronal models
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