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Finding the appropriate formulation is often challenging, labor intensive, and requires significant amount of API to test in a range of solvent v Overcoming Food Effects, Variability & Solubility for a Non-Opioid Analgesic with Lipid-Based Formulations Poorly soluble oral small molecules often face compounded development risks, including food effects, high dose requirements, variability in exposure and the need for rapid onset
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PubMed laboratory research record [PMID: 16227137] PubMed record related to this compound for laboratory literature review
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