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Results Protection from alcohol-induced steatosis and accelerated clearance of ethanol and acetaldehyde in KO mice Mice were fed a high fat liquid diet containing ethanol (EtOH) or isocaloric control (CON) diet for 6 wk
Currently, several senolytics were reported to kill senescent cells ( In this study, we tested the hypothesis that FOXO4-DRI treatment can selectively remove senescent cells in expanded human chondrocytes, thus enhancing their potential to generate high-quality cartilage
Such cells have evolved an array of antioxidant mechanisms, such as the thiol system, to combat oxidative stress, including nitric oxide, carbon monoxide, and hydrogen (per)sulfide [27]
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