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The evidence base consists primarily of animal studies with limited human clinical data

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GLP-1 plays several critical roles in glucose and appetite regulation: it stimulates insulin release from the pancreas, inhibits glucagon secretion to prevent excess glucose production, slows gastric emptying to moderate post-meal blood sugar spikes, and promotes satiety by acting on hunger centers in the brain (6)(23)

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While cagrilintide is not yet FDA-approved , its ongoing development suggests strong potential as part of a new pharmacologic framework in obesity care

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