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Price and Accessibility: Price ranges vary, and while some products are positioned as luxury treatments (Shiseido, Kiehls), others offer effective solutions at a more accessible price point (Clinique, Lancer)

Physicians may prescribe it off-label, but alternative options (Contrave, GLP-1s, Qsymia) are purpose-built

Semaglutide improves health-related quality of life versus placebo when added to standard of care in patients with type 2 diabetes at high cardiovascular risk (SUSTAIN 6)

Both of these are substantially more expensive than last year's original offer, but as Sesame touts, they are still cheaper than competitors like Hims & Hers and Ro