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In the UK, pernicious anaemia is typically treated with intramuscular hydroxocobalamin 1 mg injections following the standard NHS schedule

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SSRIs help set that process in motion

NNMTs role is to transfer a methyl group to nicotinamide (vitamin B3), creating 1-methylnicotinamide a reaction that consumes cellular methyl donors and depletes nicotinamide adenine dinucleotide (NAD) stores