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There were higher levels in the high-dose group (3035% increase vs 17% increase in the low-dose group)

PLoS Pathog 7(10):e1002290 Editor information Editors and Affiliations Rights and permissions Copyright information 2025 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd

Moreover, the NAD + depletion or the NAD + hydrolysis products induced signaling contributes to the TNT-triggered ROS production

They are not approved for human therapeutic use in Australia, and researchers are responsible for compliance with Therapeutic Goods Administration (TGA) regulations and their institution's protocols