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The non-oxidative branch not only replenishes metabolites of the oxidative branch by the reversible reactions, but also regulates the flux of glycolysis or gluconeogenesis by providing F6P and G3P (5) (Figure 1)

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It is a synthetic analog of human growth hormone (HGH), originating from the modification of the growth hormones last 16 amino acids at positions 176 to 191

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