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In turn, the interruption of BDNF signaling triggers hippocampal amyloidogenesis by promoting the accumulation of PS1 N-terminal catalytic subunits, APP C-terminal fragments, and abnormal aggregation of A [205]
A patient receiving tirzepatide 15 mg weekly, whether from a Zepbound pen or a Mounjaro pen, can expect the same pharmacokinetic profile, the same receptor-binding activity, the same clinical outcomes documented across the SURMOUNT and SURPASS programs, and the same side-effect risk
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