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Document history Updated in August 2025 by Lisa Dal Pozzo (Mechanism of Action and Safety) and the CAM Cancer Collaboration

Restore Proportion: Balancing your frame by smoothing out areas that are disproportionate to your new size

An increase in AMP/ATP ratio activates AMPK, which phosphorylates the TSC2, and this modification induces the concomitant inhibition of mTORC1 mediated by the TSC1-TSC2 complex [114]