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After the initial introduction of SGLT2i in 2013 [9] and following demonstration of kidney and cardiovascular outcome benefits for patients with type 2 diabetes, in 2021 the US Food and Drug Administration (FDA) provided the first indication that SGLT2i reduced the risk of kidney disease progression in patients with CKD [10, 11]
These medications work through GLP-1 receptor activity and must be prescribed and monitored by a licensed healthcare provider
Tirzepatide is still one of the strongest compounds in the weight-loss category and remains a benchmark
Irisin exhibits neuroprotection by preventing mitochondrial damage in Parkinsons disease
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