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Of note, as the DKP produced possesses the same mass than AX, the cyclization of the antibiotic in the presence of thiol-containing compounds would remain undetected if monitored only by MS ( Table 1 Reactivity of penicillins in presence of Dithiothreitol (DTT) in different conditions
Pantos, 2022) and ibuprofen (e.g., De Lange et al., 2006
It interacts with enzymes such as neutral endopeptidase and aminopeptidase N, which influence peptide metabolism in tissues
Generation of C-reactive protein and complement components in atherosclerotic plaques
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