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Elevated expression of IGF-IR in BCR/ABL + cells may promote the development and self-renewal of chronic myeloid leukemia, while downregulation of IGF-IR in BCR/ABL + cells leads to acute lymphoblastic leukemia (ALL) [14]

Despite the benign nature of the tumour, microscopic evidence of tumour presence at the margin of resection indicated an increased likelihood of local recurrence and the possible need for more surgery