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Seek immediate medical attention (A&E or call 999) if you develop: Severe, persistent abdominal pain radiating to the back (potential pancreatitis) Bloody or black, tarry stools Persistent vomiting with inability to keep down fluids Signs of severe dehydration or altered consciousness Symptoms of bowel obstruction (severe bloating, inability to pass gas or stool, severe cramping) For urgent but non-life-threatening concerns outside of GP hours, contact NHS 111 for advice