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Funding The authors are grateful to the National Key Research and Development Program of China (2022YFD1300701, 2019YFE0115000) and the China Agriculture Research System of MOF and MARA (CARS-41)

Therefore, the rationale for protein restriction in the CKD setting is based on the decrease in kidney overload, which leads to an improvement in renal hemodynamics by decreasing the intraglomerular pressure and glomerular hyperfiltration

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