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The biological effect also differs pulsatile vs
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10.3389/fphar.2021.627533 63 SeiwerthS.RucmanR.TurkovicB.SeverM.KlicekR.RadicB.et al (2018)
D57 (CTR) and D254 (G), were predicted protonated, however, visual inspection did not support this prediction because of their solvent-exposed location and, therefore, were modelled in the anionic side chain form
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