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2.1.3.4 Altered macrophage polarization (M1/M2 balance) Macrophages are plastic and can shift phenotypes depending on cues classically activated M1 are pro-inflammatory and microbicidal, whereas alternatively activated M2 are anti-inflammatory and involved in repair ( Figure 2 )
~ The shift is significant: Pharma is no longer just marketing products, it is competing for attention in the same way consumer brands do, participating in cultural moments that shape everyday habits and perceptions
Some people benefit most from a carefully supervised combination of the two
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