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"Constipation from GLP-1s can be compounded by the fact that people are eating less," says Hamilton, "resulting often in less fiber consumption and less stool bulk overall." Many people also drink less fluid to avoid feeling overly full on GLP-1 medications, which can also lead to constipation

Research suggests it can help improve some cholesterol markers, including lowering LDL cholesterol (often called bad cholesterol) and potentially raising HDL cholesterol (often called good cholesterol)

Loss of Muscle Mass How Muscle Loss Affects Metabolism During weight loss, particularly if the approach is overly aggressive or lacks proper protein intake and strength training, individuals may lose muscle mass alongside fat

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