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A five-year, randomized, double-blind, placebo-controlled trial in healthy Danish older people (ages at inclusion, 60-74 years) found that selenium supplementation (100-300 g/day) had little-to-no impact on circulating levels of antioxidant enzymes, including GPx (166)
Nevertheless, despite demonstrating potent in vivo effects, neither study performed side-by-side dose-response benchmarking against clinical ACE inhibitors (e.g., lisinopril or captopril) under identical assay conditions
It can build up in your arteries, contributing to calcification or hardening in your blood vessels, says the British Heart Foundation
Dosage, Administration, and What to Expect Both medicines are given as once-weekly subcutaneous injections with gradual dose titration
