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These guidelines synthesize evidence from multiple trials and provide recommendations on patient selection, dosing, monitoring, and combination therapy strategies
Treatment suitability is determined by clinical assessment
OS primarily affects three key mechanisms: (1) up-regulation of Na/K-ATPase, (2) increases water permeability while simultaneously reducing the protein reflection coefficient through the peritoneal barrier, and (3) stimulation of angiotensin-induced aldosterone secretion (137)
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