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70 In addition, substance P accelerates inflammatory signaling and is of considerable research interest in chronic pain as well as psychological conditions including depression, anxiety, and PTSD
Homocysteine and cardiovascular disease Observational studies indicate that even moderately elevated blood concentrations of homocysteine raise the risk of cardiovascular disease (CVD), although randomized controlled trials of homocysteine-lowering therapy have generally not translated to reductions in adverse cardiovascular outcomes (26, 27)
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