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IL-18 acts in synergy with IL-12 to stimulate T cells production of IFN-, which in turn stimulates synovial macrophages to produce TNF- and IL-1, leading to joint inflammation and cartilage destruction (79)
Mixing them creates stability and degradation issues that compromise the efficacy of both compounds
With this BPC-157+TB-500 PEN 10 mg + 10 mg can be described as a complex of research peptides for analyses of tissue repair mechanisms, without reference to therapeutic or functional applications
BPC-157 has accumulated an impressive safety profile in animal studies
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