GLP-1 drugs protect against new or worsening addictions, large study shows Ozempic, Mounjaro and other GLP-1 drugs for diabetes can prevent new substance use disorders and alleviate existing addictions, according to findings from a large study of U.S
Mariotti S, Zoncu S, Pigliaru F, Putzu C, Cambuli VM, Vargiu S, et al
For example, a recent study indicated that unlike in mouse islets where tirzepatide stimulates insulin secretion predominantly through the GLP-1R, the therapeutic effects of tirzepatide on human beta and alpha cells require engagement of both the GLP-1R and the GIPR, and in addition, tirzepatide increased glucagon secretion in isolated islets [207]
The theoretical concern shared by all GH-elevating compounds potential promotion of undetected existing malignancies through elevated IGF-1 applies to ipamorelin