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221,222 Ischemic necrosis of myocardial tissue triggers biomechanical changes during cardiac contraction and relaxation, which activate myofibroblasts to produce excessive collagen
Meta-analyses of large cardiovascular outcome trials have demonstrated that GLP-1R agonists, i.e., dulaglutide , liraglutide , injectable and oral semaglutide , have a potential stroke-protective effect (Pfeffer et al., 2015