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Surveys and Reports from Providers and Patients Several human studies of GLP-1s for addiction, detailed below, have been initiated following widespread reports from patients and providers of unexpected anti-addictive effects from semaglutide and tirzepatide
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Prolonged activation of GLP-1, GLP-2, and GIP receptors is achieved through receptor agonists resistant to DPP4 cleavage or through compounds that inhibit DPP4 activity (Jeppesen et al., 2005
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