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Furthermore, capillary fragility and livedo reticularis are present in loose connective tissue, leading to easy bruising in the patients affected.15,23 However, it is important to note that the European Consensus Guidelines do not include edema in the diagnostic criteria for lipedema

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The strongest responses tend to come from people who are consistent with weekly dosing, follow through on lifestyle changes alongside medication, and work with a provider to adjust dosing at the right pace