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Aunque ambos compuestos actan a travs de los mismos receptores, difieren en varios aspectos importantes: Estructura : la versin LR3 tiene una secuencia de aminocidos modificada, que incluye la sustitucin en la posicin 3 y 13 aminocidos adicionales en el extremo N-terminal, lo que aumenta su resistencia a la degradacin

Reactive O2 species molecules include peroxide (H2O2) and superoxide anions (O2 with unpaired electron) these molecules are very toxic to the cell

peripheral vascular thrombosis Hematological : Polycythemia vera (a rare type of blood cancer) Gastrointestinal : Mild, transient diarrhea Dermatological : Itching