GLP-1 Receptors Exist Throughout the Body Although GLP-1 medications work in the pancreas to regulate insulin and glucagon, GLP-1 receptors are widely distributed in other areas of the body, including the brain, cardiovascular system, immune system, gut, and kidneys, says Diana Isaacs, PharmD, CDCES, an endocrine clinical pharmacy specialist in the Endocrine and Metabolism Institute at Cleveland Clinic in Ohio
This case demonstrated how semaglutide has the potential to improve psoriasis outcomes involving both the cutaneous presentation and associated comorbidities such as cardiovascular risk
Food & Drug Administration (FDA) includes epitalon in its group of peptides that pose a risk of immunogenicity, in which the body reacts to a substance as though it were a threat and mounts an immune response against it.37 The FDA warns that such immune responses can be life-threatening, so epitalon isnt completely safe for everyone.38 In addition, the healthcare providers weve consulted suggest that women who are pregnant or breastfeeding should avoid epitalon, along with other therapeutic peptides, since there isnt enough research to confirm safety for them or their fetus/child
Longo M, Zatterale F, Naderi J, Parrillo L, Formisano P, Raciti GA, et al