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Food and Drug Administration (FDA) for diabetes treatment and not obesity

Patients should be advised to maintain consistent timing of levothyroxine administration and to report any symptoms suggestive of thyroid dysfunction, such as palpitations, tremor, anxiety (suggesting hyperthyroidism), or worsening fatigue and weight gain (suggesting hypothyroidism)

Dietary polyphenols promote growth of the gut bacterium Akkermansia muciniphila and attenuate high-fat diet-induced metabolic syndrome

By reshuffling, amplifying, and mobilizing genetic material, eccDNA provides stressed plants with a flexible mechanism to generate new functional diversity and adapt to environmental challenges