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Indirectly, smoking can lead to secondary polycythemia due to increased carboxyhemoglobin levels, which reduces the oxygen-carrying capacity of the blood and results in tissue hypoxia [11, 12]
Side effects are uncommon and usually mild, such as temporary flushing or soreness at the site
J Cell Physiol 165 (2), 307312
This convenience makes it an attractive option for people with busy lifestyles or those who prefer a non-invasive approach to supplementation
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