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Furthermore, our results demonstrated greater consistency in hazard ratios between the censored and non-censored analyses and narrower CIs for the TTE approach, compared to the MMRM approach

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In each of the three dosing periods, after the last metformin dose and the last digoxin dose, PK samples were collected for 30 and 120 h, respectively (Electronic Supplementary Table 1)

Three different rodent diets (Table 1) were provided ad libitum to 20 animals each (Research Diets, Inc., New Brunswick, USA)