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We recently described that 25% of GBM patients present genetic alterations in the genes encoding ser/gly synthesis enzymes [21], observing common PSPH amplifications (cBioPortal, TCGA PanCancer Atlas dataset) (Figure S1) [25]
MT-1s clinical development as Afamelanotide for erythropoietic protoporphyria
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This accelerated titration must be done carefully and only under provider supervision
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