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Additionally, TFR1, acyl-CoA synthetase family member 2 (ACSF2), and heme oxygenase-1 (HO-1) expression were significantly upregulated, leading to increased ferroptosis in the optic nerves of locally demyelinated MS mice
Such hyper-inflammatory state could lead to loss of appetite, altered intestinal absorption, impaired gut permeability, and malnutrition 683,684
When used at normal doses, they complement each other and are safe to combine
Wolfgang Marik: declares no conflict of interest relevant to this study
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