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Review Papakonstantinou E, Ryan DH, Harris RB
Variants in genes encoding glutathione-synthesis enzymes (like GCLC or GSS) or detoxification machinery may indicate stronger biological rationale for considering glutathione intervention
Compared to the GLP-1 receptor agonist semaglutide and placebo, tirzepatide demonstrated superior reductions in HbA1c (2.05%) and body weight (11.2kg) over 28 weeks
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