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The therapeutic activity of Ginkgo extracts is related mainly into two groups of bioactive metabolites: terpene lactones (Ginkgolides A, B, C and J and bilobalide) and ginkgo flavones (quercetin, kaempferol, and isorhamnetin glycosides as the main flavonoids) together with bioflavonoids
MAPK/ERK Proliferation Pathway IGF-1 LR3 also activates the mitogen-activated protein kinase (MAPK/ERK) signaling pathway through Ras-Raf-MEK-ERK activation
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Smith GA et al
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