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Following subcutaneous injection, the peptide rapidly enters systemic circulation with peak concentrations achieved in approximately three to six minutes
The STEP trial program examining higher-dose semaglutide (2.4 mg weekly) for weight management demonstrated mean weight loss of 12% to 15% over 68 weeks in adults with obesity, significantly exceeding placebo
This concentration works best for higher doses where the rounding error becomes proportionally smaller
It is found mainly in red meat, fish, and dairy products, in addition to being synthesized by the body
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