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Gerbild, H., Larsen, C

Such interaction between the ECM and the actin cytoskeleton through integrins allows integrins to maintain cytoskeletal organization, cell motility and intracellular-signaling pathways such as cell survival, cell shape, cell proliferation, and angiogenesis (Luo et al., 2007)

DeMario MD, Ratain MJ

In short, long-term, high-dose L-carnitine use can lead to higher levels of this compound, which is linked to an increased risk of: Atherosclerosis Heart attacks Stroke There have also been concerns raised about seizures in earlier reports, though current reviews havent found solid evidence that L-carnitine causes them