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Week 1 Some participants may begin noticing nausea, reduced appetite, early fullness, mild stomach discomfort, or bloating during the first week after starting treatment or following a dose increase

Poret JM, Souza-Smith F, Marcell SJ, Gaudet DA, Tzeng TH, Braymer HD, et al

Blood Sugar and Weight Management During Corticosteroid Courses Prednisone raises blood glucose by increasing hepatic glucose production and reducing insulin sensitivity, an effect that develops within hours of the first dose

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