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Plasma concentrations are highest in childhood and decline with age, which is part of why GHK-Cu shows up frequently in skin-regeneration, wound-healing, and aging-biology research as both an endogenous reference compound and a candidate study tool in cell-based models
The non-enzymatic system includes antioxidant molecules such as ascorbate (ASC), glutathione (GSH), tocopherols, proline, flavo- noids, carotenoids, phenolic compounds, cytochromes and polyamines (Ahmad et al
Vitamin B12 is needed for red blood cell production, DNA synthesis, and normal nerve function
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