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In the same study, ozonated oil was found to promote the differentiation of basal keratinocytes in psoriasis-like dermatitis mouse model by increasing the P63 mediated transcription of keratin 10 ( KRT10 ) gene, a marker of physiological epidermal differentiation, and downregulating the expression of keratin 6 ( KRT6 ), a marker of epidermal hyperproliferation (Gao et al