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B12 is present in a variety of food sources (mainly animal-based products), where it is bound to protein molecules

In comparison, commercially available GLP-1 patches cost $10 to $25 for a 30-day supply (without insurance)

MMA can be treated with cobalamin injections on an individual basis, and long-term treatment includes the use of special formulas limiting the precursor substances of propionic acid (methionine-, valine-, threonine-, and isoleucine-free): high-calorie diets are provided to support growth and development, carnitine supplementation is recommended to promote organic acid excretion, and application of antibiotics can be used to reduce the intestinal flora

Rotating injection sites regularly helps minimize this issue