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At screening, the mean duration of diabetes was approximately 12 years, the mean BMI was approximately 31 kg/m2, mean eGFR was 80.6 mL/min/1.73 m2 and 86.1% of patients had an eGFR 60 mL/min
The theory is that continuous high-dose GLP-1 agonist exposure can lead to partial receptor desensitization, and a brief period at a lower dose allows the receptors to upregulate
The supplement form of cysteine is called N-Acetyl Cysteine
The researchers caution that patients should not expect GLP-1 drugs to become arthritis treatments anytime soon
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