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It should be noted that evidence for HF specifically from the CVOTs are all associated with a number of limitations
E.et al (2023)
Management strategies include slower dose titration and temporary dose reduction if needed
STEP-HFpEF Trial Committees and Investigators, Kosiborod MN, Abildstrm SZ, Borlaug BA, Butler J, Rasmussen S, Davies M et al (2023) Semaglutide in patients with heart failure with preserved ejection fraction and obesity
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