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Yes, many patients do

Other pharmacological options may include GLP-1 receptor agonists such as semaglutide (Wegovy), orlistat, or naltrexone/bupropion (Mysimba), though similar considerations regarding post-surgical use apply and specialist assessment is required

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This event then triggers the activation of genes associated with the differentiation of BMSCs into osteoblasts, leading to their transformation into bone-forming cells