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It produced slightly better A1c reduction than Byetta BID in head-to-head trials and with less frequent nausea after initial weeks ( [61] ) ( [101] )
Similarly, the Cardiac and Metabolic Effects of Semaglutide in Heart Failure With Preserved Ejection Fraction study focuses on obese patients with HFpEF to evaluate improvements in cardiac structure, exercise tolerance, and metabolic health [64]
To minimise problems: Sip water regularly and aim for around 2 to 3 litres per day, unless your doctor advises otherwise Consider water rich foods such as soups, cucumbers and watermelon Start with smaller meals, eating slowly and stopping at the first sign of comfortable fullness Focus on softer, easy to digest foods if you feel unwell 4
Pancreatic considerations: GLP-1 agonists increase pancreatic enzyme output
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