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Permeability was calculated as follows: where P app represents the Caco-2 permeability, dQ/dt refers to the amount of drug in the basolateral side by time (mol/s), A refers to the area of the Transwell plate (cm 2 ), and C 0 refers to the initial concentration of drug on the apical side (mol/mL)
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Eligibility in India generally means a BMI of 2730 with a metabolic complication (such as PCOS, fatty liver, or prediabetes) or a BMI above 30, alongside uncontrolled Type 2 diabetes, abdominal obesity, or strong family history of metabolic disease
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